Appendix

Appendix MCP Server

Appendix turns any AI health conversation into a physician-reviewed opinion, with a prescription if you need one.

Your agent writes a medical encounter summary, submits it through our API, and a real doctor signs off.

Use the Appendix MCP server to search medical literature, submit clinical encounters, and receive clinical guidance and prescriptions from board-certified physicians. Learn more at appendix.com.

Installation

Claude Code

claude mcp add --transport http appendix https://mcp.appendix.com/mcp

Claude Desktop / Claude Web Connectors

Add to your Claude Desktop config (claude_desktop_config.json) or Claude.ai custom-connector form:

{
  "mcpServers": {
    "appendix": {
      "url": "https://mcp.appendix.com/mcp"
    }
  }
}

Other clients

Client	URL
Claude Code, Claude Desktop, Claude.ai connectors	https://mcp.appendix.com/mcp
Anthropic Messages API (mcp_servers)	https://mcp.appendix.com/mcp

The server speaks Streamable HTTP only — the current MCP spec transport (2025-03-26).

Available Tools

Tool	Description
search_knowledge_base	Search medical literature and treatment guidelines
submit_encounter	Submit a clinical letter for physician review
list_conditions	List available conditions and medications

Development

npm install
npm run build
npm start

Watch mode:

npm run dev

Environment Variables

Variable	Default	Description
API_BASE_URL	https://api.appendix.com	Appendix API base URL
PORT	3001	HTTP listener port

Endpoints

Method	Path	Purpose
GET	/health	Render health probe
POST GET DELETE	/mcp	Streamable HTTP transport (stateless mode)